These distinctive diseases also share several features - this review highlights promising approaches

LAM and pulmonary Langerhans cell histiocytosis (PLCH) are rare diseases that lead to progressive cystic destruction of the lungs. Despite their distinctive characteristics, these diseases share several features.

In this review, the recent advances in the understanding of the molecular development of both these diseases, as well as the current and most promising biomarkers and therapeutic approaches, are described.

Read: New insights into lymphangioleiomyomatosis and pulmonary Langerhans cell histiocytosis, Torre, Olga; Elia, Davide; Caminati, Antonella; Harari, Sergio; European Respiratory Journal 2017; 26